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Life Scientists, All Other Salary: Massachusetts vs South Carolina

Life Scientists, All Other earn a median of $125,260 in Massachusetts and $169,440 in South Carolina. That is a nominal gap of $44,180 (-26.1%), with South Carolina paying more before any cost-of-living adjustment.

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics survey, May 2025 estimates. Cost-of-living adjustment uses BEA Regional Price Parities, most recent release.

$125,260
Massachusetts median
$118,441 after COL
$169,440
South Carolina median
$180,738 after COL
-26.1%
Nominal gap
South Carolina leads
-34.5%
Adjusted gap
South Carolina leads after COL

The story behind the numbers

On raw wages, South Carolina pays $44,180 more per year than Massachusetts for life scientists, all other, a gap of +26.1%.

After adjusting for cost of living, South Carolina still comes out ahead, with roughly $62,297 of extra purchasing power (+34.5% real gap). Local prices do not reverse the nominal advantage.

Full breakdown by location

Detailed wage, employment, and cost-of-living figures for life scientists, all other in each location. Click through to the full local salary page for percentiles, outlook, and peer areas.

Life Scientists, All Other

Massachusetts

Median salary
$125,260
Mean salary
$131,800
Employment
100
Location quotient
0.55
Jobs per 1,000
0.0
COL-adjusted median
$118,441
Regional Price Parity
105.8%

Exact state RPP match.

Full Life Scientists, All Other page for Massachusetts →

Life Scientists, All Other

South Carolina

Median salary
$169,440
Mean salary
$166,780
Employment
N/A
Location quotient
N/A
Jobs per 1,000
N/A
COL-adjusted median
$180,738
Regional Price Parity
93.7%

Exact state RPP match.

Full Life Scientists, All Other page for South Carolina →

Related pages

Keep digging into life scientists, all other from a different angle.

Common questions about this comparison

What does the cost-of-living adjustment actually do? +

It divides each location's nominal median wage by its Regional Price Parity (RPP), which measures how local prices compare to the national average (100 = national). A wage of $100,000 in an area with RPP 120 has the same purchasing power as roughly $83,000 nationally.

Why would the nominal and adjusted winners disagree? +

High-cost metros often pay higher salaries, but not by enough to fully offset the higher cost of housing, goods, and services. When that happens, the location with the lower nominal wage actually offers more real purchasing power.

What is a location quotient? +

The location quotient measures how concentrated an occupation is in a given area versus the national average. A value of 2.0 means the occupation is twice as common there as nationally. It is a signal of what a state specializes in.